Contents
Pref•ce vii
1
PART
BASIC PRINCIPLES
Intnxhxtion 1
- Pharmacodynamics
16 - Pharmacokinetics 26
- Drug 35
- Pharmac%enomics 41
AUTONOMIC DRUGS 47 - Introduction to Autonomic
Pharmacology 47
7• Cholinoceptor-Activating &
Cholinesterase-Jnhibiting Drugs 60
Cholin•xqtor Blockers & Cholinesterase
Regenerators 69 - 76
Adren«eptor 85
CARDIOVASCULAR DRUGS 93
J J Drugs Used in Hypertension 93 - Drugs Used in the Treatment of Angina
Pectoris 103
J 3. Drugs Used in Heart Fanure 112
Antiarrhythmic Drugs 122 - Diuretics & Other Drugs That Act
on the Kidney 134
PART
DRUGS WITH IMPORTANT ACTIONS
ON SMOOTH MUSCLE 145 - Histamine, Serotonin, Drugs Used in
Ergot Alkaloids, & Other Drugg
Used in Migraine 145 - Vasoactive 155
- Prostaglandins & Other Eicosanoids 162
- Nitric Oxide, Ihnors, & InhiMtors 169
- Drugs Bed in Asthma & Chronic
Obstructive Pulmonary Diwase 173
DRUGS THAT ACT IN THE
CENTRAL NERVOUS SYSTEM 183
21′ Intnxluction to CNS Pharmacol%Y 183 - Sdative•Hypnotic Drugs 190
23, Alcohols 198 - Antiseizure Drugs 205
2.5. General Anesthetics 214 - Local Anesthetics 222
27′ Skeletal Muscle 227
28 Drugs in Parkinq)nistn &
Other Movement Disorders 235 - Antipsychotic & Disorder
Agents 243
is, CONTENTS
Antidepressants 2S2
31, Opioid Analgesics & Antagonists
- Drugs Of Abuse 269
PART
DRUGS WITH IMPORTANT ACTIONS
ON BLOOD, INFLAMMATION, &
GOUT 277 - Agents in Cyt0FĂĽs; Hemat0B)ietic
Growth Factors 277 - Drugs Used in Coagulation Disorders 286
- Agents in Dydipidemia 298
NSAIDs, Acetaminophen, & Drugs t%ed in
Rheumatoid Arthritis &Gout 307
VII
PAR T
ENDOCRINE DRUGS 319 - Hypothalamic & 319
Thyroid & Antithyroid Drugs 328 - Adren«orticosteroids & Adrencxortical
Antagonists 334
•O. Gonadal Hutluunes - Pancreatic Hormones, Antidial*tic Drugs,
& Glucagon 352 - Agents That Affrct Mineral
Homeostasis
VIII
PAR T
CHEMOTHERAPEUTIC DRUGS 371 - Beta-Lactam Antibiotics & Other Cell
Wall- & Membrane-Active
Antibiotics 372
Tetracyclines’ Macrolides’ Clind•myun,
Chloramphenicol, Mreplogramins, &
Oxazolidinones 381 - Aminoglycosides & 3D
- Sulfonamides, Trirnethoprim, &
Fluorupinolones 394 - Drugs 401
- Antifungal Agents 408
- Antiviral Agents 415
Miscellaneous Antimicrobial Agents &
Disinfectants, Antiseptics, & Sterilants 42
51• Clinical Use of Antimicrobial Agents 434 - AntiprotounlDrugs 440
- Clinical Of the
Antihelminthic Drugs 449 - Cancer Chemotherapy 455
- Immur*armacology 467
PAR T
TOXICOLOGY 481
56′ Enviruunental & (kcuFtioml
481 - Hevy Metals & 487
- Management of the poioned Patient 03
x
PART
SPECIAL TOPICS 501 - Drugs Used in Gastrointestinal
Disorders
d), Cannabinoid Drugs 511
Medications 514

62.
Mechanisms 519
Appendix I. Strategies for Improving Test
Performance 525
Appendix II. Key Words for Key Drugs 528
CONTENTS
Appendix Vvamin.tinn 1
Appendix Examination 2 $8
573