Section 1: Cellular Physiology, 1
Bruce M. Koeppen and Bruce A. Stanton
1 Principles of Cell and Membrane Function, 2
2 Homeostasis: Volume and Composition of
Body Fluid Compartments, 17
3 Signal Transduction, Membrane Receptors,
Second Messengers, and Regulation of Gene
Expression, 35
Section 2: The Nervous System, 51
Eric J. Lang and Kalman Rubinson
4 The Nervous System: Introduction to Cells
and Systems, 52
5 Generation and Conduction of Action
Potentials, 65
6 Synaptic Transmission, 84
7 The Somatosensory System, 108
8 The Special Senses, 127
9 Organization of Motor Function, 161
10 Integrative Functions of the Nervous
System, 208
11 The Autonomic Nervous System and Its
Central Control, 226
Section 3: Muscle, 241
James M. Watras
12 Skeletal Muscle Physiology, 242
13 Cardiac Muscle, 268
14 Smooth Muscle, 280
Section 4: The Cardiovascular System, 300
Achilles J. Pappano and Withrow Gil Wier
15 Overview of Circulation, 301
16 Elements of Cardiac Function, 304
17 Properties of the Vasculature, 345
18 Regulation of the Heart and Vasculature, 386
19 Integrated Control of the Cardiovascular
System, 410
Section 5: The Respiratory System, 433
Michelle M. Cloutier and Roger S. Thrall
20 Introduction to the Respiratory System, 434
21 Static Lung and Chest Wall Mechanics, 447
22 Dynamic Lung and Chest Wall Mechanics, 456
23 Ventilation, Perfusion, and Ventilation/
Perfusion Relationships, 466
24 Oxygen and Carbon Dioxide Transport, 480
25 Control of Respiration, 489
26 Nonphysiological Functions of the Lung: Host
Defense and Metabolism, 498
Section 6: Gastrointestinal Physiology, 510
Kim E. Barrett and Helen E. Raybould
27 Functional Anatomy and General Principles
of Regulation in the Gastrointestinal
Tract, 511
28 The Cephalic, Oral, and Esophageal
Phases of the Integrated Response
to a Meal, 520
29 The Gastric Phase of the Integrated Response
to a Meal, 529
30 The Small Intestinal Phase of the Integrated
Response to a Meal, 541
31 The Colonic Phase of the Integrated Response
to a Meal, 559
32 Transport and Metabolic Functions of
the Liver, 568
Section 7: The Renal System, 580
Bruce A. Stanton and Bruce M. Koeppen
33 Elements of Renal Function, 581
34 Solute and Water Transport along the
Nephron: Tubular Function, 603
35 Control of Body Fluid Osmolality and
Volume, 623
36 Potassium, Calcium, and Phosphate
Homeostasis, 647
37 Role of the Kidneys in the Regulation of
Acid-Base Balance, 670
Section 8: The Endocrine and
Reproductive Systems, 685
Bruce A. White and John R. Harrison
38 Introduction to the Endocrine System, 686
39 Hormonal Regulation of Energy
Metabolism, 698
40 Hormonal Regulation of Calcium and
Phosphate Metabolism, 722
41 The Hypothalamus and Pituitary
Gland, 733
42 The Thyroid Gland, 753
43 The Adrenal Gland, 766
44 The Male and Female Reproductive
Systems, 787