Satyanarayana Biochemistry-4th Edition pdf book free download

Table of Contents

• Cover image
• Title page
• Copyright
• Preface to the Fourth Edition
• Preface to the First Edition
• Acknowledgements
• Scope of Biochemistry

Section One: Chemical Constituents of Life

• Chapter 1: Biomolecules and the Cell
• Summary
• The cell
• Eukaryotic cell
• Chapter 2: Carbohydrates
• Summary
• Monosaccharides—structural aspects
• Structure of glucose
• Disaccharides
• Polysaccharides
• Homopolysaccharides
• Heteropolysaccharides
• Agar and pectins
• Glycoproteins
• Self-assessment excercises
• Chapter 3: Lipids
• Summary
• Fatty acids
• Essential fatty acids
• Triacylglycerols
• Phospholipids
• Glycolipids
• Lipoproteins
• Steroids
• Amphipathic lipids
• Soaps and detergents
• Self-Assessment excercises
• Chapter 4: Proteins and Amino Acids
• Summary
• Amino acids
• Structure of proteins
• Self-assessment excercises
• Chapter 5: Nucleic Acids and Nucleotides
• Summary
• Nucleotides
• Structure of DNA
• Organization of DNA in the cell
• Structure of RNA
• Self-assessment excercises
• Chapter 6: Enzymes
• Summary
• Historical background
• Nomenclature and classification
• Chemical nature and properties of enzymes
• Factors affecting enzyme activity
• Active site
• Enzyme inhibition
• Enzyme specificity
• Coenzymes
• Mechanism of enzyme action
• Regulation of enzyme activity in the living system
• Units of enzyme activity
• Non-protein enzymes
• Applications of enzymes
• Diagnostic importance of enzymes
• Isoenzymes
• Enzyme pattern in diseases
• Diagnostic importance of enzymes in other body fluids and tissues
• Self-assessment excercises
• Chapter 7: Vitamins
• Summary
• Individual vitamins
• Vitamin A
• Vitamin D
• Vitamin E
• Vitamin K
• Vitamin C (Ascorbic acid)
• Thiamine (Vitamin B1)
• Riboflavin (Vitamin B2)
• Niacin
• Pyridoxine (Vitamin B6)
• Biotin
• Pantothenic acid
• Folic acid
• Cobalamin (Vitamin B12)
• Vitamin like compounds
• Choline
• Inositol
• Lipoic acid
• Para aminobenzoic acid
• Bioflavonoids
• Antivitamins
• Self-Assessment Exercises

Section Two: Physiological Biochemistry

• Chapter 8: Digestion and Absorption
• Summary
• Carbohydrates
• Proteins
• Lipids
• Nucleic acids
• Abnormalities related to digestion and absorption
• Self-assessment exercises
• Chapter 9: Plasma Proteins
• Summary
• Albumin
• Globulins
• Immunoglobulins
• Blood clotting
• Self-assessment exercises
• Chapter 10: Hemoglobin and Porphyrins
• Summary
• Hemoglobin
• Hemoglobin derivatives
• Abnormal hemoglobins
• Sickle-cell anemia or sickle-cell hemoglobin
• Thalassemias
• Porphyrins
• Biosynthesis of heme
• Porphyrias
• Degradation of heme to bile pigments
• Jaundice
• Self-assessment exercises
• Chapter 11: Biological Oxidation
• Summary
• Bioenergetics
• High-energy compounds
• Biological oxidation
• Electron transport chain
• Oxidative phosphorylation
• Self-assessment exercises

Section Three: Metabolisms

• Chapter 12: Introduction to Metabolism
• Summary
• Chapter 13: Metabolism of Carbohydrates
• Summary
• Glycolysis
• Citric acid cycle
• Gluconeogenesis
• Glycogen metabolism
• Futile cycles
• Glycogen storage diseases
• Hexose monophosphate shunt
• Uronic acid pathway
• Metabolism of galactose
• Metabolism of fructose
• Metabolism of amino sugars
• Glyoxylate cycle
• Self-assessment Exercises
• Chapter 14: Metabolism of Lipids
• Summary
• Fatty acid oxidation
• Ketone bodies
• Biosynthesis of fatty acids
• Synthesis of triacylglycerols
• Metabolism of phospholipids
• Metabolism of glycolipids
• Metabolism of cholesterol
• Lipoproteins
• Metabolism of HDL
• Disorders of plasma lipoproteins
• Fatty liver
• Lipotropic factors
• Obesity
• Atherosclerosis
• Alcohol metabolism
• Self-assessment exercises
• Chapter 15: Metabolism of Amino Acids
• Summary
• Amino acid pool
• Metabolism of amino acids —general aspects
• Metabolism of ammonia
• Urea cycle
• Metabolism of individual amino acids
• Glycine
• Phenylalanine and tyrosine
• Tryptophan
• Sulfur amino acids
• One-carbon metabolism
• Branched chain amino acids
• Histidine, proline and arginine
• Lysine
• Glutamate and glutamine
• Aspartate and asparagine
• Alanine
• Serine
• Threonine
• Fate of carbon skeleton of amino acids
• Amino acids as neurotransmitters
• Biogenic amines
• Polyamines
• Self-assessment exercises
• Chapter 16: Integration of Metabolism
• Summary
• Organ specialization and metabolic integration
• Metabolism in starvation
• Chapter 17: Metabolism of Nucleotides
• Summary
• Biosynthesis of purine ribonucleotides
• Degradation of purine nucleotides
• Disorders of purine metabolism
• Biosynthesis of pyrimidine ribonucleotides
• Self-assessment exercises
• Chapter 18: Mineral Metabolism
• Summary
• Calcium
• Phosphorus
• Magnesium
• Sodium
• Potassium
• Chlorine
• Sulfur
• Iron
• Copper
• Iodine
• Manganese
• Zinc
• Molybdenum
• Cobalt
• Fluorine
• Selenium
• Chromium
• Self-assessment exercises

Section Four: Clinical Biochemistry and Nutrition

• Chapter 19: Hormones
• Summary
• Classification of hormones
• cAMP—The second messenger
• Hypothalamic and pituitary hormones
• Hypothalamic hormones
• Anterior pituitary hormones
• Posterior pituitary hormones
• Thyroid hormones
• Hormones of adrenal cortex
• Hormones of adrenal medulla
• Hormones of gonads
• The menstrual cycle
• Gastrointestinal (or gut) hormones
• Self-assessment exercises
• Chapter 20: Organ Function Tests
• Summary
• Liver function tests
• Jaundice
• Kidney (renal) function tests
• Gastric function tests
• Other organ function tests
• Self Assessment excercises
• Chapter 21: Water
• Summary
• Water and life
• Water turnover and balance
• Electrolyte balance
• Acid-base balance
• Maintenance of blood pH
• Disorders of acid-base balance
• Blood gas measurement
• Self-assessment exercises
• Chapter 22: Tissue Proteins and Body Fluids
• Summary
• Connective tissue proteins
• Contractile proteins
• Muscle proteins
• Body fluids
• Self-assessment excercises
• Chapter 23: Nutrition
• Summary
• Nutrition and energy supply
• Utilization of energy in man
• Nutritional importance of carbohydrates
• Fiber in nutrition
• Nutritional importance of lipids
• Nutritional importance of proteins
• Nutritional importance of vitamins and minerals
• Recommended dietary allowances (rda)
• Balanced diet
• Nutritional disorders
• Other nutritional disorders
• Therapeutic diets
• Nutritional status and clinical practice
• Nutrigenomics
• Self-assessment excercises

Section Five: Molecular Biology and Biotechnology

• Chapter 24: DNA-Replication
• Summary
• Replication of DNA
• Recombination
• Damage and repair of DNA
• Self-assessment exercises
• Chapter 25: Transcription and Translation
• Summary
• Transcription
• Reverse transcription
• Translation
• Protein biosynthesis
• Protein targeting
• Mitochondrial DNA, transcription and translation
• Self-assessment exercises
• Chapter 26: Regulation of Gene Expression
• Summary
• The operon concept
• Tryptophan operon
• Gene expression in eukaryotes
• Gene regulation in eukaryotes
• Epigenetic regulation of gene expression
• Self-assessment exercises
• Chapter 27: Recombinant DNA and Biotechnology
• Summary
• Basic techniques in genetic engineering
• DNA in disease diagnosis and medical forensics
• Pharmaceutical products of DNA technology
• Recombinant vaccines
• DNA Vaccines (genetic immunization)
• Transgenic animals
• Dolly – the transgenic clone
• Cloning of pet animals
• Biotechnology and society
• Self-assessment exercises

Section Six: Current Topics

• Chapter 28: Human Genome Project
• Summary
• Chapter 29: Gene Therapy
• Summary
• Ex vivo gene therapy
• Selected examples of ex vivo gene therapy
• In vivo gene therapy
• Antigene and antisense therapy
• Chapter 30: Bioinformatics
• Summary
• Chapter 31: Metabolism of Xenobiotics (Detoxification)
• Summary
• Mechanism of detoxification
• Chapter 32: Prostaglandins and Related Compounds
• Summary
• Leukotrienes
• Chapter 33: Biological Membranes and Transport
• Summary
• Chapter 34: Free Radicals and Antioxidants
• Summary
• Chapter 35: Environmental Biochemistry
• Summary
• Atmospheric (climatic) changes
• Environmental pollution
• Carcinogens
• Chapter 36: Insulin
• Summary
• Insulin
• Glucagon
• Regulation of blood glucose level (homeostasis of blood glucose)
• Hypoglycemia
• Classification of diabetes mellitus
• Chapter 37: Cancer
• Summary
• Etiology
• Molecular basis of cancer
• Tumor markers
• Characteristics of growing tumor cells
• Cancer therapy
• Prevention of cancer
• Chapter 38: Acquired Immunodeficiency Syndrome (AIDS)
• Summary

Section Seven: Basics to Learn Biochemistry

• Chapter 39: Introduction to Bioorganic Chemistry
• Isomerism
• Chapter 40: Overview of Biophysical Chemistry
• Water
• Acids and bases
• Buffers
• Solutions
• Colloidal state
• Diffusion
• Osmosis
• Donnan membrane equilibrium
• Viscosity
• Surface tension
• Adsorption
• Isotopes
• Chapter 41: Tools of Biochemistry
• Chromatography
• Electrophoresis
• Photometry—colorimeter and spectrophotometer
• Fluorimetry
• Flame photometry
• Ultracentrifugation
• Radioimmunoassay
• Enzyme-linked immunosorbant assay
• Hybridoma technology
• Chapter 42: Immunology
• The immune system
• The complement system
• The immune response
• Cytokines
• Immunity in health and disease
• Chapter 43: Genetics
• Appendix I : Abbreviations used in this Book
• Appendix II : Origins of Important Biochemical Words
• Appendix III : Common Confusables in Biochemistry
• Appendix IV : Practical Biochemistry—Principles
• Appendix V : Clinical Biochemistry Laboratory
• Appendix VI : Case Studies with Biochemical Correlations
• Appendix VII : Reference Biochemical Values

Index

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